Tamer Sharafeldin
Assistant Professor, Veterinary Pathologist
Biography
An ACVP board certified veterinary pathologist with a demonstrated history of working in veterinary diagnostic laboratories. My career in research focused in studying poultry diseases pathogenicity, pathogenesis and immune response. I experienced animal modeling and lesion scoring (Gross Pathology and Histopathology). Skilled in veterinary medicine, veterinary pathology, histopathology, vaccines trials, reverse transcription polymerase chain reaction (RT-PCR), sequencing technologies and molecular biology. Strong veterinary services professional with a Doctor of Philosophy (Ph.D.) focused in Veterinary Pathology from University of Minnesota-Twin Cities.
Education
- BVS in veterinary medicine | Zagazig University, Egypt | 2004
- MVS in veterinary pathology | Zagazig University, Egypt | 2008
- Ph.D. in veterinary medicine-veterinary pathology | University of Minnesota | 2014
- Diplomate | American College of Veterinary Pathologists
Academic and Professional Experience
Academic Interests
Academic Interests
- Veterinary diagnostic pathology
- Avian pathology/immunology/vaccinology
- Avian reovirus (Turkey reoviruses)
- Avian infectious bronchitis virus (IBV)
Academic Responsibilities
- Regular diagnostic pathology
- Research
- Teaching
Committees and Professional Memberships
Committees
- SDSU Faculty Senate
- PPVM Curriculum Committee
Professional Memberships
- American College of Veterinary Pathologists
- American Association of Avian Pathologists
Extension Responsibilities
- Turkey Industry
- Game Birds
- Backyard Small Poultry Flocks
Research and Scholarly Work
Areas of Research
- Masters of Veterinary Sciences
- Experimental study of the interaction between a vaccine strain and a very virulent strain of infectious bursal disease virus.
- Evaluation of the interaction using histopathologic lesions scoring of bursal lesions and RT-PCR/ RFLP.
- Ph.D. in Veterinary Medicine
- Studied the short- and long-term pathogenicity of Turkey arthritis reovirus (TARV) in turkeys and in chickens, virus pathogenesis and cytokine immune responses in TARV-infected turkeys.
- Further Research Experiences
- Surveillance and experimental studies to investigate the role of enteric viruses in poult enteritis complex in Minnesota.
- Diagnostic research on avian influenza virus, Newcastle disease virus and oncogenic viruses in poultry production in Egypt.
- Experience with sequencing technology, Sanger sequencing, next generation sequencing (library prep, DNA, RNA seq, data analysis).
- Vaccine research (Killed, live and recombinant vaccine development).
- Diagnostic assay development (Molecular and serologic assays).
- Surveillance to study the prevalence of different infectious bronchitis virus genotypes in Pennsylvania.
- Vaccine research for avian reovirus in the U.S.
Awards and Honors
- 2014, Graduate Student Travel Award to travel to the Western Poultry Disease Conference, Puerto Vallarta, Mexico
- 2014, Graduate Student Research Award, North Central Avian Disease Conference, Saint Paul, MN
- 2009, Partnership and Ownership (ParOwn) Award for Pathology Training, University of Minnesota Veterinary Diagnostic Laboratory
Grants
- Deploying Baculovirus Vector in Protection Against Poultry Viral Diseases with Validation of Supportive Serologic Assays. SDBOR competitive research grant, $88.349.
- Development and evaluation of a novel viral vectored vaccine to protect pigs against porcine reproductive and respiratory syndrome virus. Haarberg 3D research center, $99,597.
- Control strategies for emerging variants of turkey reovirus-USDA-NIFA AFRI, $299,907.
- Surveillance, Rapid Detection, and Characterization of SARS-CoV-2 in Farmed and Wild Animals. USDA-APHIS ARS, $2,156,152.
- Development of a serologic assay and novel vaccine approach to mitigate turkey arthritis reovirus. Minnesota Turkey Research and Promotion Council, 2021-2023, $70,000.
- Turkey Reovirus solutions, South Dakota Poultry Industry Council (SDPIC), 2021, $15,000.
- Pathogenicity and Genetic Profile of Turkey Hepatitis Reovirus (THRV). United States Poultry and Egg (USPE), 2020-2021, $64,369.
- Development and Evaluation of vaccination strategies against turkey arthritis/tenosynovitis reovirus. United States Poultry and Egg (USPE), 2018-2020, $122,804.
- Immunologic correlates of avian reovirus: developing a diagnostic and serotyping ELISA for turkey reovirus. Pennsylvania Department of Agriculture (PDA), 2019, $25,000.
- Characterization of strains of infectious bronchitis virus in Pennsylvania: Survey and molecular diagnostic technology development. Pennsylvania poultry industry research Check-Off program, 2018, $20,000.
- Studies on effects of newly emerging avian reovirus variants on egg-laying hens and efficacy of nonmetallic disinfection on reovirus. Egg Industry Council (EIC), 2018-2020, $89,917.
- Pathogenesis of newly emergent turkey arthritis reovirus in turkeys. Rapid Agriculture Response Funding (RARF), University of Minnesota, 2012-2015, $250,000.
Publications
- Kumar R., Sharafeldin T.A., Goyal S.M., Mor S.K., Porter R.E., Infection and transmission dynamics of Turkey arthritis reovirus in different age Turkeys, Microbial Pathogenesis, Volume 173, Part A, 2022.
- Kumar R., Sharafeldin T.A., Sobhy N.M., Goyal S.M., Porter R.E. and Mor S.K. (2022) Comparative pathogenesis of turkey reoviruses, Avian Pathology, 51:5, 435-444, DOI: 10.1080/03079457.2022.2079474.
- Temeeyasen G., Sharafeldin T.A., Lin C., Hause B.M. . Emerging Infectious Diseases. 2022;28(2):471-473. DOI: 10.3201/eid2802.211681.
- Kumar P., Sharafeldin T.A., Kumar R., Huang Q., Liang Y., Goyal S.M., Porter R.E., Ly H., Mor S.K. Development of a Recombinant Pichinde Virus-Vectored Vaccine against Turkey Arthritis Reovirus and Its Immunological Response Characterization in Vaccinated Animals. Pathogens. 2021 Feb 13;10(2):197. doi: 10.3390/pathogens10020197. PMID: 33668435; PMCID: PMC7918942.
- Aboubakr H.A., Sharafeldin T.A., Goyal S.M. . Transbound Emerg Dis. 2020; 00: 1–17. DOI: 10.1111/tbed.13707.
- Sharafeldin T.A., Mor S.K., Goyal S.M., Porter R.E. Altered Biomechanical Properties of Gastrocnemius Tendons of Turkeys Infected with Turkey Arthritis Reovirus. Veterinary Medicine International 2016. DOI: 10.1155/2016/7829138.
- Sharafeldin T.A., Mor S.K., Abdel-Glil M.Y., Goyal S.M. Prevalence of turkey parvovirus in Minnesota turkeys. Poultry Science 2016 doi: 10.3382/ps/pew283.
